Are you passionate about cutting-edge biophysical research? Join the Laboratory of Biophysics at the Department of Optical and Biophysical Systems, Institute of Physics of the Czech Academy of Sciences! We are dedicated to unraveling how physical factors, such as novel nanomaterials and mechanical forces within the cell microenvironment, impact cellular machinery.
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Our current research focuses on “The impact of extracellular mechanical cues on interactions between DNA nanostructures and hepatic cells.” DNA nanotechnology has revolutionized the creation of novel composite materials with diverse applications in biomedicine. To bridge the gap between these innovations and their real-world applications, it is crucial to understand how DNA nanostructures interact with living cells and the subsequent effects of these interactions. Our goal is to explore the molecular and biophysical mechanisms that influence the uptake and processing of DNA nanostructures by cells under external mechanical forces. We will investigate the cellular processing of these nanostructures, including their transport mechanisms, organelle interactions, and degradation pathways.
We invite enthusiastic students to join our dynamic team. Whether you're at the beginning of your academic journey or further along, we offer a rich learning experience tailored to your level of expertise.
What you will do:
- Engage in cell culturing, characterization, and analysis of cell lines
- Set up and conduct experimental work to explore exciting scientific questions in modern biophysics)
Required qualifications:
- Pursuing a degree in cell biology, biochemistry, biology, or a related discipline (junior or senior standing)
- Possess strong analytical and problem-solving skills
- Capable of delivering on project timelines, both independently and in team settings
- Effective communicators, both verbally and in writing
What we can offer:
We are committed to providing a stimulating and supportive environment. Here’s what you can expect:
Learning Opportunities: Gain hands-on experience with advanced laboratory techniques and methods, including:
- Conventional confocal and super-resolution live cell imaging
- Cell culturing
- Cytotoxicity studies
- Cell signaling analysis
- Protein function analysis
- Gene editing and expression analysis
International and Friendly Environment: Join a diverse team of researchers in a well-equipped lab with state-of-the-art facilities
Professional Growth: Develop your analytical and problem-solving skills while working on impactful projects
Excellent PhD Program: Student will be appointed to “Biochemistry and Pathobiochemistry” PhD program at the 1st Faculty of Medicine of the Charles University, Prague
Terms of employment:
- Start of employment as soon as possible, depending on the availability of the applicant
- Full-time job with flexible hours, extended vacations, work from home, and a wide range of other benefits
- 1-year contract with possible extension
Application procedure:
- Interested candidates are invited to apply by sending a CV and a motivation letter, including a publication record to kariera [at] fzu [dot] cz
- For further information please contact HR partner