Laser irradiation and cellular responses


A burst of research in this direction resulted in therapeutic applications of low power red and near-infrared light to promote wound healing, hair growth, tissue regeneration, reduce pain, etc. However, many of such investigations are hampered by shortcomings in experimental design and often also by a lack of reproducibility. Thus, rigorous research of detailed biophysical mechanisms of laser-cell interactions are of a great value.
Additionally, similar high fluence low-power laser irradiation is utilized in super-resolution localization microscopy. Unfortunately, so far live-cell super-resolution localization microscopy largely ignored possible phototoxic effects. Therefore, we aim to understand the molecular basis that drives phototoxic effects to be able to significantly improve imaging techniques.

Theme is contributed to by

Mgr. Adam Frtús

Pracovní pozice
Research and Development Specialist
+420 266 05 2491