Drug induced liver injury - FZU hosted a debate about a serious problem

Abstract

Active substances of drugs, alone or in combination with each other, herbs and herbal supplements are metabolized by the human liver. This metabolization can be associated with irreversible damage or even death of the patient. There is no effective prevention against this problem. Additionally, there is no simple drug testing preclinical system to decipher hepatotoxicity issues undoubtfully at early stages of the drug development.

Brain4Industry supports Czech companies in the implementation of technology and scientific knowledge

Abstract

Savings in material and operating costs, less waste, added product value, greener operation. The positive results achieved by Czech manufacturing companies thanks to the collaboration with the Brain4Industry (B4I) consortium, the main coordinator of which is the Institute of Physics of the Czech Academy of Sciences, became the main theme of the Společná cesta k digitalizaci českých výrobců (Joint Journey of Czech Manufacturers towards Digitization) conference, which was organized on Wednesday, March 1, by B4I in partnership with the Czech Management Association.

Collaboration between science and business in TACR Théta programme has brought progress in the area of heat exchange

Abstract

Scientists from the Institute of Physics of the Czech Academy of Sciences in collaboration with BENEŠ a LÁT a.s. and CARDAM s.r.o. managed to develop a cooling system for complex forms manufactured by means of 3D printing. The project results utilize the latest findings in the area of coating technologies and significant progress of additive manufacturing. 

DNA nanotechnology on the rise

Abstract

Scientists from the Laboratory of Biophysics contributed to the field of DNA nanotechnology with a recent systematic analysis. The authors, led by Oleg Lunov, have summarized the current state of knowledge about the interactions of DNA nanostructures (DN) with cells and identified the key challenges.

FZU researchers are taking part in developing a system for a timely detection of melanoma in humans

Abstract

A device that uses a single blood drop to determine whether a patient has a melanoma, and, possibly, at what stage, is being developed by an international research team that includes researchers from the Institute of Physics of the Czech Academy of Sciences led by the researcher Jakub Dostálek. As part of the VerSiLiB project, they are building a device capable of capturing and detecting even very small amounts of molecules produced by tumour cells, which can be used as biomarkers.

We Will be Developing Nanorobots

Abstract

He likes to play with light, to put it bluntly.  Jakub Dostálek, who is the latest acquisition of the Optics Division, focuses on investigating material properties and how they affect light. Or the other way round – how light affects material properties and the ways to control such properties using light. Having worked for over ten years abroad, he is now taking his first steps to return to Czechia.

The Optics Division were betting on interdisciplinary research and time proved them right – everything has come together to run like a well-oiled machine

Abstract

“We had the opportunity to invest time into interdisciplinary research, knowing that if everything works according to plan, we‘ll rank among the best. But an overarching element of our research remains to be optics – we’ve never run away from it,” says Alexandr Dejneka, the Optics Division Head, in an interview. 

The Radius Development Centre is opening up to students

Abstract

A combination of theoretical study, purposeful work, and valuable practical experience – this is what the Radius Development Centre provides to university students. The centre was conceived by three Institutes of the Academy of Sciences together with two universities – Palacký University in Olomouc and University of South Bohemia in České Budějovice.

The study proved Czech scientist’s biochip to fast and reliably detect SARS-CoV-2

Abstract

The biochip is as fast as an antigen test and at the time as reliable as the PCR method. A team of Czech scientists led by Hana Lísalová has achieved the most crucial milestone in the development of a unique system for the detection of the SARS-CoV-2 virus causing COVID-19. Biosensor research, which the system is based on, confirmed their sensitivity and reliability and opened new options for further development in this area.