Electron crystallography focuses on structure determination using electron radiation, electron diffraction in particular.
Electron diffraction in comparison to X-ray diffraction can be performed on very small samples (nanocrystals) that would diffract the X-ray only very poorly. On the other hand, interaction of electrons with atoms in a crystal is much more complex than X-ray diffraction, and thus structure analysis using electron diffraction is computationally demanding method, and until recently, also less accurate compare to X-ray structure analysis. Our group focuses on the development of experimental and computational methods applied in electron crystallography. The core of our laboratory is a transmission elektron microscope FEI Tecnai G2 20. This microscope has a large sample tilt up to ±70°, which is crucial for examining the 3D structure of crystals. Microscope is equipped with an attachment DigiStar (NanoMegas) that generates the precession motion of the beam, and by a CCD detector Veleta for collecting electron diffraction data.
Method of dynamical refinement of electron diffraction data developed in GEC allows for locating even the lightest atoms - hydrogen atoms, shown as yellow isosurfaces in the potential map and overlaid with the structure model of paracetamol (A) and cobalt aluminophosphate (B).