Spinal cord injury (SCI) is a condition that results in significant mortality and morbidity. In this study, we designed a magnetic system and used it to accumulate stem cells labelled with superparamagnetic iron oxide nanoparticles (SPION) at a specific site of a SCI lesion. The results suggest that focused targeting and fast delivery of stem cells can be achieved using the proposed non-invasive magnetic system. With future implementation, the proposed targeting and delivery strategy bears advantages for the treatment of diseases requiring fast stem cell transplantation.
An effective strategy of magnetic stem cell delivery for spinal cord injury therapy