A new study by scientists led by Oleg Lunov of the Division of Optics of the Institute of Physics of the Czech Academy of Sciences sheds light on how a cell's shape and mechanics influence its absorption of drug carriers.
After two and a half years of intensive work, scientists from the Laboratory of Biophysics of the Institute of Physics of the Czech Academy of Sciences, led by Oleg Lunov, have presented a breakthrough DNA nanostructure based platform, which allows for the targeted influence of lysosomal functions in cells.
Active substances of drugs, alone or in combination with each other, herbs and herbal supplements are metabolized by the human liver. This metabolization can be associated with irreversible damage or even death of the patient. There is no effective prevention against this problem. Additionally, there is no simple drug testing preclinical system to decipher hepatotoxicity issues undoubtfully at early stages of the drug development.
